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China has a high burden of CA due to its large population, especially given the increasing maternal age with the adjustment of birth policies [10]. Screening for and prenatal confirmation of CA have also developed rapidly in China. Our previous study revealed an increased prevalence of trisomy 21 in Zhejiang Province, located in eastern China [10]. However, several previous studies have focused on the efficacy of screening methods and calculated the prevalence of CA in live births or were restricted to numerical CA. Zhejiang Province has a well-established hospital-based birth defect monitoring system that routinely collects CA information from pregnancy loss, stillbirths, and newborns. This study provides insights into the comprehensive epidemiology, prenatal diagnosis, and estimation of birth outcomes of CA in Zhejiang, as well as updates of our previous findings, and may provide a reference for CA prevention and intervention in other developing countries.

In this case, we cannot directly code a birth date and complete a gap analysis. It is to show that gap analysis can be further strengthened by moving from the stage of first detected CA to the stage of the last dispensed treatment. Therefore the issue of the distances between detected time and treatment dispensation is not anticipated anymore.

Born into thisWalking and living through thisDying because of thisMuted because of thisCastratedDebauchedDisinheritedBecause of thisFooled by thisUsed by thisPissed on by thisMade crazy and sick by thisMade inhumanBy thisThe heart is blackenedThe fingers reach for the throatThe gunThe knifeThe bombThe fingers reach toward an unresponsive godThe fingers reach for the bottleThe pillThe powderWe are born into this sorrowful deadliness d2c66b5586